Methodology for the Assessment of Burden of Smearpositive Pulmonary TB and Its Infectivity
- Author:
QUN XU
1
;
Zheng-Lai WU
;
XIAO-LIN LIU
;
SHUI-GAO JIN
;
LI-XING ZHANG
Author Information
1. Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sicences
- Keywords:
Tuberculosis(TB);
Burden of disease(BOD);
Disability-adjusted life year(DALY)
- From:
Biomedical and Environmental Sciences
2002;15(1):8-15
- CountryChina
- Language:Chinese
-
Abstract:
The study investigated the burden of smear-positive pulmonary TB and its infectivity using DALY(disability-adjusted life year) as an indicator. Methods An assumed cohort of 2 000 cases was set up based on the age-specific incidence of 794 newly registered smear-positive cases in Beijing in 1994. Prognostic trees and model diagrams of infectivity under natural history and DOTS(directly observed treatment, short-course) strategy were established according to the epidemiological evidence. Results The results showed that 29.6%of DALYs would be neglected if the burden caused by the infectivity was not considered.Conclusion DOTS strategy may reduce 97.3% of the number of potential cases infected,92.9% of DALYs related to TB-patients themselves. and 99.9% of DALYs caused by TB's infectivity as well.
