Tuberculosis control priorities defined by using cost-effectiveness and burden of disease.
- Author:
Qun XU
1
;
Zheng-Lai WU
;
Shui-Gao JIN
;
Li-Xing ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Child; Child, Preschool; China; epidemiology; Cohort Studies; Cost of Illness; Cost-Benefit Analysis; Disabled Persons; Forecasting; Humans; Middle Aged; Models, Biological; Quality-Adjusted Life Years; Tuberculosis; economics; epidemiology; prevention & control
- From: Biomedical and Environmental Sciences 2002;15(2):172-176
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo define TB control priorities using cost-effectiveness and burden of disease.
METHODSAn assumed cohort of 2,000 cases was set up based on age-specific incidence of 794 newly registered smear-positive cases in Beijing in 1994. Prognostic trees and model diagrams of infectivity with natural history and DOTS intervention were constructed based on the epidemiological parameters.
RESULTSDOTS reduced 89.19% of YLL, 78.90% of YLD, and 99.98% of infectivity BOD. One DALY could be saved with 45.70 Yuan by DOTS with 3% discount. Sensitivity analysis showed that discount had effect on CER. Weight of age was insensitive to CER. The higher the DOTS cured rate, the more the cost-effectiveness.
CONCLUSIONSDOTS is a good cost-effectiveness TB control strategy. Cost-effectiveness and burden of disease can be used to define TB control priorities.
