Effect of electro-acupuncture on calcium content in neurocytes of focal cerebral ischemia.
- Author:
Neng-gui XU
1
;
Wei YI
;
Xin-sheng LAI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Biological Transport, Active; Brain; metabolism; pathology; Calcium; metabolism; Electroacupuncture; Infarction, Middle Cerebral Artery; metabolism; pathology; Male; Microscopy, Confocal; Neurons; metabolism; Random Allocation; Rats; Rats, Wistar
- From: Chinese Journal of Integrated Traditional and Western Medicine 2002;22(4):295-297
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of electro-acupuncture (EA) in regulating calcium (Ca2+) content in brain neurocytes of rats with focal cerebral ischemia.
METHODSThe changes of Ca2+ content in ischemic neurocytes were observed by using laser confocal scanning microscope.
RESULTSCa2+ content did not change significantly in cerebral cortex when the brain ischemia occurred for 1 hr, but it raised significantly in striatum neurocytes. Both the Ca2+ contents in striatum and cortex area increased significantly 3 hrs after ischemia occurrence and the content in striatum was higher than that in cortex significantly. Brain Ca2+ content could be reduced significantly after the 3 hrs ischemic brain were treated by EA for 30 min.
CONCLUSIONEA could regulate the content of Ca2+ in the ischemic area of brain, inhibit Ca2+ overload, so as to protect neurons from ischemic injury.
