Effect of gandou tablet I on neurological electrophysiology in patients of hepatolenticular degeneration.
- Author:
Wen-bin HU
1
;
Ren-min YANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Child; Drugs, Chinese Herbal; therapeutic use; Electroencephalography; drug effects; Electromyography; drug effects; Electrophysiology; Evoked Potentials, Auditory, Brain Stem; drug effects; Hepatolenticular Degeneration; drug therapy; physiopathology; Humans; Male; Phytotherapy; Tablets
- From: Chinese Journal of Integrated Traditional and Western Medicine 2002;22(1):14-17
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the influence of Gandou Tablet I (GD I) on neurologic electrophysiology in patients of hepatolenticular degeneration (HLD).
METHODSVigilance-controlled electroencephalogram (VEEG), electromyogram (EMG) and brain-stem auditory evoked potential (BAEP) in 32 cases of HLD were examined before GD I treatment, and reexamined after 4 weeks of treatment in those with abnormal neurologic electrophysiology.
RESULTSAt the same time of clinical symptom improvement after treatment, the abnormal VEEG, EMG and BAEP also improved with the effective rate of 71.43%, 70% and 66.67% respectively, their constitutional ratio were different insignificantly, P > 0.05. The peak latency (PL) of III, V waves and interpeak latency (IPL) of I-III, III-V and I-V waves in patients before treatment were all greatly prolonged, compared with those in the healthy control group (P < 0.05 or 0.01), the IPL of III-V and I-V waves were markedly improved after treatment.
CONCLUSIONNeurologic electrophysiologic examination was valuable for complementary diagnosis and therapeutic effect evaluation of HLD. GD I could improve the abnormal neurologic electrophysiologic parameters.
