Effect of bushen huayu composite on secretion of lymphocytic interleukin-2 and interleukin-2 receptor expression in the aged.

Author: Rong-rong WANG ¹ ; Su-bin LIU
Author Information

1. Department of Integrated Traditional and Western Medicine, First Hospital of Peking University, Beijing 100084.
Publication Type:Journal Article
MeSH: Adjuvants, Immunologic; pharmacology; Aged; Aging; drug effects; immunology; Drugs, Chinese Herbal; pharmacology; Female; Humans; Interleukin-2; blood; Lymphocytes; immunology; Male; Middle Aged; Phytotherapy; Receptors, Interleukin-2; blood
From:Chinese Journal of Integrated Traditional and Western Medicine 2002;22(1):25-27
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the effect of Bushen Huayu Composite (BSHY) on interleukin-2 (IL-2) secretion and IL-2 receptor expression in the aged.
METHODSIL-2 was examined by methyl thiazolyl tetrazolium (MTT) method and IL-2 dependent cellular stains, IL-2 receptor expression was examined by FACS-indirect immunofluorescence.
RESULTSAging could result in the decrease in lymphocytic IL-2 secretion and IL-2 receptor expression (P < 0.01, P < 0.05), which could be improved by BSHY (P < 0.01, P < 0.05).
CONCLUSIONBSHY has significant up-regulatory effect on immune function of lymphocytes in the aged.