Effect of bushen huayu composite on secretion of lymphocytic interleukin-2 and interleukin-2 receptor expression in the aged.
- Author:
Rong-rong WANG
1
;
Su-bin LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adjuvants, Immunologic; pharmacology; Aged; Aging; drug effects; immunology; Drugs, Chinese Herbal; pharmacology; Female; Humans; Interleukin-2; blood; Lymphocytes; immunology; Male; Middle Aged; Phytotherapy; Receptors, Interleukin-2; blood
- From: Chinese Journal of Integrated Traditional and Western Medicine 2002;22(1):25-27
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of Bushen Huayu Composite (BSHY) on interleukin-2 (IL-2) secretion and IL-2 receptor expression in the aged.
METHODSIL-2 was examined by methyl thiazolyl tetrazolium (MTT) method and IL-2 dependent cellular stains, IL-2 receptor expression was examined by FACS-indirect immunofluorescence.
RESULTSAging could result in the decrease in lymphocytic IL-2 secretion and IL-2 receptor expression (P < 0.01, P < 0.05), which could be improved by BSHY (P < 0.01, P < 0.05).
CONCLUSIONBSHY has significant up-regulatory effect on immune function of lymphocytes in the aged.
