Clinical observation on colquhounia root tablet in treating lipid metabolism disturbance secondary to nephrotic syndrome.
- Author:
Xin-lin WU
1
;
Jun-biao LI
;
Sui-lin MO
Author Information
- Publication Type:Clinical Trial
- MeSH: Adolescent; Adult; Aged; Cholesterol; blood; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Hyperlipidemias; blood; drug therapy; etiology; Lipoproteins, HDL; blood; Male; Middle Aged; Nephrotic Syndrome; blood; complications; drug therapy; Phytotherapy; Triglycerides; blood
- From: Chinese Journal of Integrated Traditional and Western Medicine 2002;22(1):30-32
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of Colquhounia root tablet (CRT) in treating nephrotic syndrome with sequential lipid metabolism disorder (NS-LMD).
METHODSThe 96 patients with NS-LMD were randomly divided into two groups, the 60 cases in the treated group treated with CRT and the 36 cases in the control group treated with hormone or cytotoxic medicine. The curative effect and the related indexes were determined before and after treatment.
RESULTSAfter six months treatment, the general effective rate in the treated group was 88. 33%, which was markedly higher than that in the control group (69.44%, P < 0.05). The levels of the treated group in ameliorating lipid metabolism disorder and renal dysfunction were also higher than those in the control group (P < 0.05).
CONCLUSIONCRT could improve NS-LMD, improve renal function, eliminate urinary protein and increase plasma albumin. It is highly effective with low toxicity and safe.