A new cardiac glycoside from Periploca forrestii.
- Author:
Ran XU
1
;
Juan DU
;
Lulu DENG
;
Fumei YANG
;
Jianxin ZHANG
;
Daoping WANG
;
Yuanhu ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Cardiotonic Agents; chemistry; isolation & purification; Drugs, Chinese Herbal; chemistry; isolation & purification; Glycosides; chemistry; isolation & purification; Molecular Structure; Periploca; chemistry
- From: China Journal of Chinese Materia Medica 2012;37(15):2286-2288
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Periploca forrestii.
METHODThe constituents were separate using such various column chromatographic techniques as silica gel, RP-18 silica gel, MCI and Sephadex LH-20. Their structures were identified by such methods as spectral analysis.
RESULTTen compounds were isolated and identified as periforgenin A-3-O-beta-digitoxopyranoside (1), beta-sitosterol (2), periforoside I (3), ursolic acid (4), periplogenin (5), periplocin (6), glycoside E (7), periplocoside M (8) , daucosterol (9), 2alpha, 3alpha, 23-trihydroxy-urs-12-en-28-oic acid (10).
CONCLUSIONCompound 1 was a new cardiac glycoside and compound 8 was reported for the first time from this plant.
