A new natural product from root of Angelica dahurica cv. Qibaizhi.
- Author:
Aihong ZHAO
1
;
Xiuwei YANG
;
Xinbao YANG
;
Jianxun LIU
;
Qiuling WANG
;
Wenquan WANG
Author Information
- Publication Type:Journal Article
- MeSH: Angelica; chemistry; China; Coumarins; chemistry; isolation & purification; Drugs, Chinese Herbal; chemistry; isolation & purification; Furocoumarins; chemistry; isolation & purification; Molecular Structure; Plant Roots; chemistry
- From: China Journal of Chinese Materia Medica 2012;37(16):2400-2407
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of the root of Angelica dahurica cv. Qibaizhi.
METHODThe compounds were isolated and purified by the methods of solvent extraction and chromatographic technique, and their structures were identified on the basis of the analyses of spectral data.
RESULTTwenty-seven compounds were obtained and identified as isoimperatorin (1), alloisoimperatorin (2), oxypeucedanin hydrate (3), byakangelicin (4), alloimperatorin (5), beta-sitosterol (6), dibutylphthalate (7), 6-(3,3-dimethylallyloxy) -7-hydroxycoumarin {7-hydroxy-6-[ (3-methyl-2-butenyl) oxy] -coumarin, 8}, xanthotoxol (9), 5-hydroxy-8-methoxypsoralen ( 5-hydroxyxanthotoxin, 10), smyrindiol (11), umbelliferone (12), bergapten (13), imperatorin (14), phellopterin (15), isoimpinellin (16), 6-acyl-7-methoxycoumarin (17), psoralen (18), isoscopletin (19), scoparone (20), xanthotoxin (21), angelol A (22), oxypeucedanin ethanolate (oxypeucedanin hydrate-3"-ethyl ether, 23), dehydrogeijerin (pablohopin, 24) , ulopterol (25), heraclenol (26), and pabulenol (27), respectively.
CONCLUSIONCompound 8 was a new natural product and the above-mentioned all the compounds except for compounds 1, 3 and 14 were isolated from the root of A. dahurica cv. Qibaizhi for the first time.
