Advance in anticancer studies on catechins and their derivatives.
- Author:
Jie ZHOU
1
;
Zheng-li GONG
;
Kai ZHANG
;
Yang-ping DING
Author Information
1. College of Food Science, Southwest University, Chongqing 400716, China. zjgigi@swu.edu.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Antineoplastic Agents, Phytogenic;
chemistry;
pharmacology;
Catechin;
chemistry;
pharmacology;
Humans;
Neoplasms;
drug therapy;
metabolism;
prevention & control;
Plant Extracts;
chemistry;
pharmacology;
Signal Transduction;
drug effects
- From:
China Journal of Chinese Materia Medica
2012;37(17):2510-2518
- CountryChina
- Language:Chinese
-
Abstract:
Experimental studies on animals discovered that catechins have a notable inhibitory effect on the formation and development of tumors in different organs. Studies on their mechanism showed that catechins could inhibit cancer cell invasion and proliferation, angiogenesis and metastasis and induce cancer cell apoptosis through anti-oxidation and by inhibiting related enzyme activities and cancer cell signal transmission. This essay provides an overview of correlation between tea drinking and cancer prevention, various mechanisms of catechins and their derivatives such as biochemical cancer prevention and anticancer and looks into the future of catechins.
