Removal of cadmium from extracts of Gentianae Radix et Rhizoma by gamma-mercaptopropyl-modified silica gel.
- Author:
Liang-mian CHEN
1
;
Cai-zhi KUANG
;
Hui-min GAO
;
Qi-wei ZHANG
;
Zhi-min WANG
;
Jing-jing ZHU
;
Yan-qing LU
Author Information
- Publication Type:Journal Article
- MeSH: Adsorption; Cadmium; chemistry; Drug Contamination; Gentianaceae; chemistry; Rhizome; chemistry; Silica Gel; chemistry
- From: China Journal of Chinese Materia Medica 2012;37(17):2548-2553
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the optimum process of removing cadmium irons from extracts of Gentianae Radix et Rhizoma with gamma-mercaptopropyl-modified silica gel (MPS) and assess its cadmium ion-removing property.
METHODStatic and dynamic adsorptions were adopted to detect the cadmium-removing rate. MPS' cadmium ion-removing property was assessed with such indicators as the cadmium-removing rate, the solid content and the HPLC fingerprint.
RESULTThe process parameters of the static adsorption were as follows: 0.20 g x mL(-1) of concentration of extracts, 120 minutes of adsorption time and 15:1 between raw materials and MPS. The process parameters of the dynamic adsorption were as follows: 1:3.5 times between diameter and height, 0.20 g x mL(-1) of concentration of extracts, 0.9 mL x min(-1) of flow rate of the extracts and 50:1 between raw materials and MPS. Before and after the cadmium ion-removing process, the extracts showed no notable difference in solid content and HPLC fingerprint.
CONCLUSIONgamma-mercaptopropyl-modified silica gel (MPS) can effectively remove cadmium ion from the extracts of Gentianae Radix et Rhizoma with an excellent cadmium ion-removing property.
