Cyclopeptides from Rubia schumanniana.
- Author:
Bin KUANG
1
;
Jun-ting FAN
;
Si-meng ZHAO
;
Ning-hua TAN
Author Information
- Publication Type:Journal Article
- MeSH: Drugs, Chinese Herbal; chemistry; isolation & purification; Molecular Structure; Peptides, Cyclic; analysis; isolation & purification; Rubia; chemistry
- From: China Journal of Chinese Materia Medica 2012;37(17):2563-2570
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo separate and identify cyclopeptides of tubers of Rubia schumanniana.
METHODThe 70% methanol extracts from tubers of Rubia schumanniana were separated and purified by silica gel, RP-18, Sephedax LH-20 and HPLC. Their structures were identified by spectral analysis.
RESULTNine cyclopeptides were separated and identified as RA- II (1), RA-V (2), RA-VIII (3), rubiyunnanin C (4), RA-X (5), RY-II (6), RA- I (7), RA-XIII (8) and RA-XIII-OMe (9), respectively.
CONCLUSIONAll of nine cyclopeptides were separated from R. schumanniana for the first time.
