HLA-DRB1 polymorphism in the Ewenki Ethnic of Inner Mongolian.
- Author:
Rong HAI
1
;
Li-fu BI
;
Xiu-lan SU
Author Information
- Publication Type:Journal Article
- MeSH: Asian Continental Ancestry Group; genetics; China; ethnology; Ethnic Groups; HLA-DR Antigens; genetics; HLA-DRB1 Chains; Humans; Polymorphism, Genetic
- From: Chinese Journal of Medical Genetics 2006;23(1):95-96
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the HLA-DRB1 genetic polymorphism in the Ewenki of Inner mongolia.
METHODSHLA-DRB1 allele polymorphisms in 84 normal Ewenki were determined by PCR with sequencing based typing (SBT).
RESULTSTwenty-five HLA-DRB1 alleles were observed. The allele frequency of HLA-DRB1*03011(14.88%) is the highest; the allele frequencies of HLA -DRB1*09012 (13.69%), DRB1*07011(8.92%), DRB1*04011(9.52%) and DRB1*12011(8.33%) are lower.
CONCLUSIONThe distribution of HLA-DRB1 alleles frequencies in normal Ewenki from Inner Mongolia exhibits a unique profile, which is of important reference value for studies on anthropology and related illnesses in Ewenki population.
