The genetic polymorphism of 9 short tandem repeat loci in Yi ethnic group of Yunnan in China.
- Author:
Ya GAO
1
;
Tian-bo JIN
;
Jiang-hua LAI
;
Hai-bo ZHENG
;
Sheng-bin LI
Author Information
- Publication Type:Journal Article
- MeSH: Asian Continental Ancestry Group; genetics; China; ethnology; Chromosome Mapping; Ethnic Groups; genetics; Genetics, Population; Humans; Microsatellite Repeats; genetics; Polymorphism, Genetic; Tandem Repeat Sequences
- From: Chinese Journal of Medical Genetics 2006;23(2):216-218
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the short teadem repeat(STR) genetics structure of a Chinese Yunnan Yi racial group.
METHODSGenetic distributions for nine STR loci were determined based on STR gene scan marked by fluorescence.
RESULTSSixty-nine alleles and 164 kinds of genotypes were detected and identified from 84 unrelated Yi racial individuals. The corresponding gene and genotype frequencies were in 0.0060-0.5060 or 0.0119-0.4167 respectively. The expected and observed genotype frequencies of nine STR loci were in accordance with the Hardy-Weinberg equilibrium(P>0.05). The statistical analyses of nine STR loci showed that PIC was distributed in 0.5804-0.8777, H was in 0.6507-0.8002, DP was in 0.7976-0.9558, EPP was in 0.5207-0.8386, except TPOX and THO1 loci.
CONCLUSIONAbove research data enrich the Chinese genetic database, and play an important role in Chinese genetic study and in forensic application.