The research progress of using electroporation therapy in treatment of tumor.
- Author:
Chenguo YAO
1
;
Caixin SUN
;
Lan XIONG
;
Yan MI
;
Lina HU
Author Information
1. College of Electrical Engineering, Chongqing University, Chongqing 400044.
- Publication Type:Journal Article
- MeSH:
Cell Membrane;
ultrastructure;
Electrochemotherapy;
Humans;
Neoplasms;
drug therapy;
Research;
trends
- From:
Journal of Biomedical Engineering
2002;19(2):337-339
- CountryChina
- Language:Chinese
-
Abstract:
In these years, the electrical technology is widely applied in the study of biomedical engineering. Using electroporation therapy (EPT) to treat tumor is associated with biomedical engineering, electrical new technology, computer technology and microelectronic technology, which is a new marginal subject. Many experts have studied the mechanism and clinical treatment of the cell membrane electroporation phenomenon under electrical fields. These researches have shown that the membrane electroporation can stimulate the transport and intake of various drugs, which improves the tumoricidal effect of these drugs. The researchers have also been exploring the phenomenon that irreversible electrical breakdown (IREB) of cell membrane under high electrical fields and steep pulses leads to the death of tumor.
