Psychiatric and central nervous system involvement in Sjogren's syndrome.

Yan Wang; Song-ling Wang; Yi-zhuang Zou; Guo-ming Luan

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Psychiatric and central nervous system involvement in Sjogren's syndrome.

Author: Yan WANG ¹ ; Song-ling WANG ; Yi-zhuang ZOU ; Guo-ming LUAN
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1. Salivary Gland Disease Center, Beijing Hospital for Stomatology, Capital University of Medical Sciences, Beijing 100050, China.
Publication Type:Journal Article
MeSH: Adult; Aged; Electroencephalography; Female; Humans; MMPI; Magnetic Resonance Imaging; Middle Aged; Sjogren's Syndrome; diagnostic imaging; physiopathology; psychology; Ultrasonography, Doppler, Transcranial
From:Chinese Journal of Stomatology 2004;39(2):158-160
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study psychiatric features and the manifestations of central nervous system involvement in Chinese patients with primary Sjogren's syndrome (PSS).
METHODSThe Minnesota Multiphasic Personality Inventory (MMPI) was used to study 27 PSS female patients and 57 healthy women. The results from two groups were compared. Ten SS patients were evaluated by electroencephalography (EEG), transcranial doppler ultrasound (TCD) and magnetic resonance imaging (MRI).
RESULTSOf 27 patients tested, the three highest clinical mean scales included Hypochondriasis (Hs), Hysteria (Hy), Psychasthenia (Pt) were found. When PSS group was compared with normal control, T scores of SS patients were significantly higher than the healthy women in Hs, Hy. Abnormal EEG was found in 3 of 9 PSS patients. TCD was abnormal in 5 of 9 patients. MRI in 1 patient showed abnormality.
CONCLUSIONSThis study shows that the personality of PSS patients is abnormal, the features are neuroticism. Central nervous system was markedly involved in Chinese patients with PSS, including abnormal EEG and TCD. The changes of central nervous system may be related to abnormalities of psychiatric changes.