Using platelet-rich plasma (PRP) to improve bone regeneration in implant bone defect.
- Author:
Yu ZHANG
1
;
Ye LIN
;
Li-xin QIU
;
Xing WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Alveolar Ridge Augmentation; methods; Bone Regeneration; Bone Substitutes; therapeutic use; Bone Transplantation; methods; Female; Guided Tissue Regeneration, Periodontal; methods; Humans; Male; Maxillary Sinus; surgery; Middle Aged; Oral Surgical Procedures, Preprosthetic; methods; Platelet Transfusion; methods; Treatment Outcome
- From: Chinese Journal of Stomatology 2004;39(4):269-272
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the result of bone regeneration due to using PRP in combination with beta-TCP in bone defect adjacent to oral implantation.
METHODSTen patients (6 males, 4 females, with an average age of 49.6 years) participated in this study. Seven of them underwent maxillary sinus augmentations, and 3 underwent GBR for peri-implant bone defects. PRP + beta-TCP was used in 4 cases and beta-TCP in other 6 as control. X-ray examinations were carried out prior to operation and in 1 week, at 3 months, 6 months after operation. After 4 - 6 months, 3 biopsy specimens were obtained at the time of the second stage operation in each group.
RESULTSBone grafts healed well without any infection in all cases. Radiographs showed that bone grafts integrated together with the bone. The histological result showed that new bone was formed among particles of beta-TCP in both groups, but in PRP + beta-TCP group denser and better arranged woven bone was observed, and more new bone was formed into the micropores of the particles.
CONCLUSIONSThe result in this study implied that PRP in combination with beta-TCP can improve bone regeneration in bone defect adjacent to oral implantation.
