- Author:
Ki Sung MIN
1
;
Daeseok HAN
;
Sang Oh KWON
;
Kyung Mok YEO
;
Bok Nam KIM
;
Sun Yung LY
Author Information
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords: Sargassum confusum; reduction of body fat ratio; overweight women
- MeSH: Adipose Tissue*; Body Composition; Defecation; Electric Impedance; Female; Humans; Intra-Abdominal Fat; Leptin; Overweight; Surveys and Questionnaires; Risk Factors; Sargassum*; Tablets; Waist Circumference
- From:Journal of Nutrition and Health 2014;47(1):23-32
- CountryRepublic of Korea
- Language:Korean
- Abstract: PURPOSE: This study was conducted in order to investigate the effect of Sargassum confusum extracts on the reduction of body fat for eight weeks in overweight women (BMI > or = 23 kg/m2). METHODS: Subjects were classified by double-blind randomized trial as the control group (C group, n = 14) and the Sargassum confusum extract supplementation group (SC group, n = 16), which consumed 12 tablets per day. Questionnaires related to their health status were assessed twice (week 0 and week 8). Their dietary intake status was evaluated by 24-recall method and body compositions were measured using a bioelectrical impedance analyzer. In addition, we assessed the anti-obesity effect and the occurrence possibility of health risk factors during the supplementation periods by hematological and clinical analysis of blood. RESULTS: Waist circumference and body fat (%) were significantly decreased in the SC group. Serum leptin level was also significantly decreased in the SC group. Defecation frequency was significantly increased in the SC group. The above results indicate that Sargassum confusum extract supplementation improves overweight on visceral fat and blood leptin level by increasing bowel movement. These results imply a decrease of health risk factors in overweight women. Seven subjects withdrew from the study due to adverse events; however, no differences regarding adverse events were observed between the control and treatment group. CONCLUSION: Therefore, Sargassum confusum extract is a plausible effective agent for body fat reduction in humans.