Rare blood group screening by serological and molecular methods in Zhejiang Han population.
- Author:
Hong ZHU
1
;
Ying LIU
;
Xiao-Zhen HONG
;
Xiao-Guo XU
;
Xiao-Fei LAN
;
Kai-Rong MA
;
Ji HE
;
Fa-Ming ZHU
;
Hang-Jun LU
Author Information
1. Blood Center of Zhejiang Province, Hangzhou, Zhejiang Province, China.
- Publication Type:Journal Article
- MeSH:
Asian Continental Ancestry Group;
genetics;
Blood Group Antigens;
genetics;
Blood Grouping and Crossmatching;
methods;
Erythrocytes;
immunology;
Humans;
Molecular Biology;
Phenotype
- From:
Journal of Experimental Hematology
2012;20(3):749-752
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to investigate the distribution of rare blood group in Zhejiang Han population. The H(-) (H system), GPA(-) and s(-) (MNS), Rhnull, Rhmod, D--, CCDEE, CCdEE (variations of Rh), GPC(-) (Gerbich), i(+) (I), Lu(b-) (Lutheran), Js(b-) and k(-) (Kell), Fy(a-) (Duffy), Ok(a-) (Ok), Di(b-) (Diego) phenotypes were screened by serological or molecular methods. Jk (a-b-) phenotype was detected by urea hemolytic test. The results showed that one Di (a+b-) individual was found in 1618 blood donors, three Fy (a-b+) individuals in 1007 donors and one CCdEE individual in 633 Rh negative donors. No Jk (a-b-), H(-), GPA(-), s(-), GPC(-), i(+) (adult), Lu(b-), k(-), Js(b-), Lu(b-) and Ok(a-) phenotypes were found in this large scale survey. It is concluded that Di (a+b-), Fy (a-b+), CCdEE phenotypes are confirmed in the blood donors and this study provides the distribution data of erythrocyte rare blood group in Zhejiang Han population.
