Cellular Schwannoma of the Cervical Spine in an Infant: A Case Report.
- Author:
Oon Ki BAEK
1
;
Ki Uk KIM
;
Seo Hee RHA
;
Jong Geun KIM
;
Hyu Jin CHOI
;
Hyung Dong KIM
Author Information
1. Department of Neurosurgery, College of Medicine, Dong-A University, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Cellular schwannoma;
Spinal cord tumor;
Infant
- MeSH:
Female;
Humans;
Infant*;
Laminectomy;
Magnetic Resonance Imaging;
Neurilemmoma*;
Peripheral Nerves;
Quadriplegia;
S100 Proteins;
Spinal Cord Neoplasms;
Spine*
- From:Journal of Korean Neurosurgical Society
1998;27(6):831-836
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cellular schwannoma is a very rare benign tumor involving peripheral nerves, mimicking malignant nerve sheath tumor in histological appearance. It is a clinico-pathological variant of benign schwannoma characterized by a high cellularity, increased mitotic figures and occasional presence of bone destruction. A 6-month-old female patient was admitted with progressive quadriparesis. Magnetic resonance imaging of the cervical spine showed a well-enhancing extramedullary mass on the C4 to C6 area. Total laminectomy was performed on C4-7, and intradural extramedullary tumor was removed. Histologically, the tumor was composed of proliferated spindle cells. Most of the tumor was composed of Antoni A area with hypercellular spindle cells arranged in fascicular pattern. The tumor cells showed mild atypism with mitotic figure upto 4/10HPF and diffuse, strong S-100 protein immunostaining. The patient was improved postoperatively.