Result of Postoperative Radiotherapy of the Rectal Cancer.
- Author:
Moon June CHO
1
;
Sung Whan HA
;
Charn Il PARK
;
Kuk Jin CHOE
;
Jin Pok KIM
Author Information
1. Department of therapeutic Radiology, College of Medicine, Seoul National University, Korea.
- Publication Type:Original Article
- Keywords:
Rectal cancer;
Post-op radiotherapy
- MeSH:
Adenocarcinoma;
Humans;
Incidence;
Lymph Nodes;
Neoplasm Metastasis;
Radiotherapy*;
Radiotherapy, Adjuvant;
Rectal Neoplasms*;
Rectum;
Recurrence;
Retrospective Studies
- From:Journal of the Korean Society for Therapeutic Radiology
1986;4(2):147-154
- CountryRepublic of Korea
- Language:English
-
Abstract:
To assess the effect of postoperative radiotherapy on tumor recurrence and patient survival, 133 patients who received adjuvant postoperative radiotherapy for adenocarcinoma of the rectum were retrospectively analyzed. Sixty-one percent of the patients were in stage C2 by Astler-Coller staging system. A significant statistical difference was noticed in failure rates for lymph node negative vs lymph node positive patients;26%(9/35) vs 50%(49/98). The incidence of local failure was found to be strongly dependent on the pathologic stages; with 9%(3/35) of recurrence in stage B and 21% (21-98) in stage C. Distant metastasis has occurred in 29% (38/133) of the patients; 2% (7/35) in stage B and 32%(31-98) in stage C. The actuarial Survival at 3 years for patients in stage B2, stage C1, and stage C2, were 78%, 47%, and 38%, respectively. In conclusion, the postoperative adjuvant radiotherapy for rectal carcinoma appears to reduce local recurrence significantly.
