Regional cerebral oxygen saturation in neonates with meconium aspiration syndrome.
- Author:
Zhi-Guang LI
1
;
Wen-Fang YE
;
Fei-Qiu WEN
;
Hai-Shu DING
Author Information
- Publication Type:Journal Article
- MeSH: Brain; metabolism; Female; Humans; Hypoxia-Ischemia, Brain; metabolism; Infant, Newborn; Male; Meconium Aspiration Syndrome; metabolism; Oxygen; metabolism; Spectroscopy, Near-Infrared
- From: Chinese Journal of Contemporary Pediatrics 2006;8(3):191-194
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThis study examined the changes of regional cerebral oxygen saturation (rSO2) by noninvasive near infrared spectrophotometry in neonates with meconium aspiration syndrome (MAS).
METHODSSeventy-three full neonates with MAS were divided into three groups by respiratory symptoms: asymptomatic group (group 1, n=38), common group (group 2, n=28) and severe group (group 3, n=7). Near infrared spectrophotometry was used to measure the cerebral rSO2 on days 1, 3, 5 and 7 after birth. Thirty healthy full-term newborns served as the Control group.
RESULTSThe cerebral rSO2 of group 1 decreased significantly compared with that of the Control group between days 1 and 3 (P < 0.05). The cerebral rSO2 of group 2 or group 3 was significantly lower than that of group 1 and the Control group on days 1, 3 and 5 (P < 0.05). The MAS patients with mild hypoxic-ischemic encephalopathy (HIE) had significantly higher brain rSO2 levels than those with medium or severe HIE on days 2, 3 and 5 (P < 0.05).
CONCLUSIONSThe cerebral rSO2 decreased in neonates with MAS. The values for rSO2 correlated with the severity of HIE in MAS patients.
