Evaluation of the function of autotransplanted parathyroid tissues.
- Author:
Guo-hui XU
1
;
Nai-song ZHANG
;
Yun-tao SONG
;
Wen-bin YU
;
Wei WEI
;
Jun-yong SUN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Case-Control Studies; Female; Humans; Male; Middle Aged; Parathyroid Glands; transplantation; Thyroidectomy; methods; Transplantation, Autologous; Treatment Outcome; Young Adult
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(8):668-671
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the function autotransplanted parathyroid tissues in thyroid surgery.
METHODSThe control group comprised 120 volunteers with normal parathyroid glands in whom serum parathyroid hormone (PTH) levels in blood samples taken from the bilateral elbow head veins. The experimental group comprised 34 patients in whom the parathyroid glands, which were mistakenly cut or could not be preserved during thyroid surgery because of ischemia, were fragmented and autografted into the brachioradialis muscle of the nondominant forearm. On the day of surgery and at 3 days, 7 days, and 2 months postoperatively, contrast imaging and detection of serum PTH levels were performed to evaluate the function of the transplanted parathyroid tissues.
RESULTSIn the control group, the mean value of the difference between the bilateral brachiocephalic vein PTH levels was (1.19 ± 0.98) ng/L (maximum 4.52 ng/L). In this study, twice the maximum value (9.04 ng/L) was taken as the effective standard. Based on the 9.04 ng/L effective value, the effective number was 26 patients and the effective rate was 76.5% at 2 months postoperatively in the 34 patients of the experimental group.
CONCLUSIONSThe autotransplanted parathyroid tissues showed their functions in most patients, therefore, parathyroid gland autotransplantation is an effective method of preserving function of parathyroid glands that are free or severely ischemic in thyroid surgery.