Influence of visual and auditory masking on the brain glucose metabolism in an idiopathic tinnitus patient

VernacularTitle:视听觉屏蔽对特发性耳鸣患者脑内葡萄糖代谢分布的影响
Author: Ming LI ¹ ; Zhe-Min HUANG ; Chuan-Tao ZUO ; Jian-Ning ZHANG
Author Information

1. 上海中医药大学附属岳阳中西医结合医院
Keywords: Tinnitus; Positron-emission tomography; Brain chemistry; Visual cortex; Auditory cortex
From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(9):720-723
CountryChina
Language:Chinese
Abstract: Objective To study the influence of the audio-visual block (AB) on the brain glucose metabolism of idiopathic tinnitus patients.Methods The brain positron emission tomography (PET) test was performed on one chronic idiopathic tinnitus patient under audio-visual block and non-block (NB) conditions respectively.The visual analysis and statistical parameter mapping(SPM) analysis were both used to detect the brain glucose metabolism difference under AB and NB conditions.Results Under NB conditions,significant hyperactivity was detected at auditory and visual cortex on both sides of the brain.However,this phenomenon was not shown under AB conditions.Instead,a hyperactivity of brain was presented in the left Wernicke’s area.Conclusions The generation of chronic idiopathic tinnitus probably has no relationship with the auditory cortex abnormity.Wernicke’s area might be involved in the central perception of tinnitus.