Relationship between the tinnitus frequency and the effects of medication and the prognosis in patients with chronic subjective tinnitus
10.3760/cma.j.issn.1673-0860.2012.09.006
- VernacularTitle:慢性主观性耳鸣患者耳鸣频率与药物治疗效果及预后的关系
- Author:
Yang LIU
1
;
Li-Sheng YU
;
Lin-Lin YU
;
Jun HAN
;
Jing-Ning CHENG
;
Da-Zhang YANG
Author Information
1. 卫生部中日友好医院
- Keywords:
Tinnitus;
Drug therapy;
Prognosis
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2012;47(9):724-727
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of tinnitus frequency on medication and prognosis in patients with chronic subjective tinnitus.Methods Seventy-two patients (Ninety-three ears) diagnosed as chronic subjective tinnitus were studied from October 2010 to March 2011.All cases were divided into low frequency (twenty-three ears ),medium frequency (fourteen ears ) and high frequency (fifty-six ears) according to tinnitus matching test.All cases were treated with microcirculation promotion and steroid therapy (5％ glucose 250 ml + ginkgo biloba extract 87.5 mg + dexamethasone 10 mg intravenous drip).Curative effect was evaluated and the factors of prognosis were analyzed after three weeks.Results After medication,results were acquired as follows:recovery in 0 ear ( 0％ ),excellent in 0 ear (0％),effective in 18 ears( 19.4％ ),invalid in 75 ear(80.6％ ).The effective percentage was 39.1％,35.7％ and 7.1％,respectively.There was significant difference between these groups,but no significant difference between low frequency and medium frequency.Logistic regression analysis showed that the difference of frequency was significant prognostic factors for medication.Conclusions Microcirculation promotion and steroid therapy had a poor treatment effect in patients with chronic subjective tinnitus.The prognosis of chronic low-medium frequency tinnitus was better than chronic high frequency tinnitus.The difference of frequency retained significant influence on effects and prognosis of medication.
