Relationship between bacterial biofilm and chronic rhinosinusitis: a systematic review

VernacularTitle:细菌生物膜与慢性鼻-鼻窦炎相关性的系统评价
Author: Sheng-Lan LI ¹ ; Shi-Ming CHEN ; Yu XU ; Yong-Gang KONG ; Ren-Yue DENG ; Ze-Zhang TAO
Author Information

1. 430060,武汉大学人民医院耳鼻咽喉头颈外科
Keywords: Biofilms; Sinusitis; Meta-analysis
From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(12):1021-1026
CountryChina
Language:Chinese
Abstract: Objective To evaluate the relationship between bacterial biofilm (BBF) and chronic rhinosinusitis(CRS).Methods The database on line was searched to collect the studies on BBF and CRS.The method of meta analysis was used to analyze the data of suitable studies.Results Fourteen studies were included.System evaluation indicated that the BBF detection rate in CRS group was significantly higher than that in the control group (OR =17.01,P ＜0.01),and the nasal surgery's rate of BBF positive group was significantly higher than the negative group (OR=3.99,P ＜ 0.01).Preoperative Lund-Kennedy endoscopic score,Lund-MacKay CT score,symptom severity score,postoperative Lund-Kennedy score after six months showed no difference between BBF positive group and negative group.Conclusion The presence of BBF is related to the pathogenesis of CRS and the history of nasal surgery.