Treatments of stage-Is testicular mixed germ cell tumors: A report of 3 cases.
- Author:
Jiang-ze WANG
;
Shan-shan HU
;
Lin-mei ZHANG
;
Teng-feng CHEN
- Publication Type:Case Reports
- MeSH: Adult; Carcinoma, Embryonal; pathology; Endodermal Sinus Tumor; pathology; Humans; Lymph Node Excision; Male; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Germ Cell and Embryonal; pathology; surgery; Orchiectomy; Retrospective Studies; Seminoma; pathology; Teratoma; pathology; Testicular Neoplasms; pathology; surgery
- From: National Journal of Andrology 2016;22(5):437-441
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate different treatment methods for stage-Is testicular mixed germ cell tumors (TMGCTs).
METHODSWe retrospectively analyzed the clinical data about 3'cases of stage-Is TMGCTs (aged 26-39 years) treated in the 175th Hospital of PLA, reviewed relevant literature, and explored the clinical characteristics of TMGCTs.
RESULTSOf the 3 patients, 1 was treated by radical orchiectomy, 1 by radical orchiectomy + retroperitoneal lymph node dissection + BEP chemotherapy scheme, and the other by radical orchiectomy + radiotherapy. The pathological components of TMGCTs were immature teratoma, seminoma, spermatocytoma, chorioepithelioma, embryonal carcinoma, and yolk sac tumor. No recurrence or distant metastasis was found during the 24-month follow-up after surgery.
CONCLUSIONThe diagnosis of TMGCTs primarily depends on physical examination, ultrasonography, MRI, and measurement of serum tumor markers, while its confirmation necessitates pathological examination, and its treatment is basically radical orchiectomy.