Diagnostic value of high-field MRI for Peyronie's disease.
- Author:
Huan-Jun WANG
1
;
Jian GUAN
2
;
Jin-Hua LIN
2
;
Bi-Tao PAN
2
;
Chun-Hua DENG
3
;
Yan GUO
2
Author Information
- Publication Type:Journal Article
- Keywords: Peyroine's disease; erectile dysfunction; magnetic resonance imaging; ultrasonography
- MeSH: Calcinosis; diagnostic imaging; Fibrosis; Humans; Magnetic Resonance Imaging; instrumentation; methods; Male; Penile Induration; diagnostic imaging; Penis; diagnostic imaging; pathology; Sensitivity and Specificity; Ultrasonography
- From: National Journal of Andrology 2016;22(9):787-791
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the MRI manifestations of Peyronie's disease and investigate the value of high-field MRI in the diagnosis of the disease.
METHODSUsing a small surface coil, we performed 3.0 Tesla MRI for 14 patients with clinically diagnosed Peyronie's disease. The MRI protocol included routine sequences (T1WI, T2WI, and enhanced T1WI) and susceptibility-weighted imaging (SWI). Each patient had received 2－4 penile ultrasound examinations previously. We compared the MRI findings with the results of ultrasonography.
RESULTSMRI manifested 25 penile plaques in the 14 patients, 3 (7 plaques) with inflammation, 4 (8 plaques) with fibrosis, and the other 7 (10 plaques) with calcification displaying a low signal intensity on SWI. Ultrasonography had revealed the 10 calcified plaques in all the 20 examinations, but exhibited the 7 inflammatory and 8 fibrotic ones in only 3 of the 23 examinations. The combination of MRI SWI sequences was necessitated for the detection of calcified plaques and achieved higher detection rates than ultrasonography for inflammatory and fibrotic plaques (P<0.05).
CONCLUSIONSHigh-field MRI has high sensitivity and accuracy in the diagnosis of Peyronie's disease, which can effectively display penile plaques of different nature in the early stage through multi-parametric sequences.
