Impact of unilateral cryptorchidism on the levels of serum anti-müllerian hormone and inhibin B.

Shun-shun Cao; Xiao-ou Shan; Yang-yang HU

Return

Impact of unilateral cryptorchidism on the levels of serum anti-müllerian hormone and inhibin B.

Author: Shun-Shun CAO ¹ ; Xiao-Ou SHAN ¹ ; Yang-Yang HU ²
Author Information

1. Department of Endocrinology and Inherited Metabolism of Children, The Second Hospital Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
2. Center of Reproductive Medicine, The Second Hospital Affiliated to Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
Publication Type:Journal Article
Keywords: anti-müllerian hormone; inhibin B; unilateral cryptorchidism
MeSH: Anti-Mullerian Hormone; blood; Case-Control Studies; Cryptorchidism; blood; pathology; Humans; Infant; Inhibins; blood; Male; Orchiopexy; Organ Size; Penis; pathology; Testis; pathology; physiopathology; Transforming Growth Factor beta
From: National Journal of Andrology 2016;22(9):805-808
CountryChina
Language:Chinese
Abstract:
ObjectiveTo investigate the influence of unilateral cryptorchidism on the levels of serum anti-müllerian hormone (AMH) and inhibin B in children.
METHODSWe enrolled 65 patients with unilateral cryptorchidism and 45 healthy children in this study. We measured the length and circumference of the penis, the testis volume in the cryptorchidism side, and the levels of serum AMH and inhibin B at the age of 6 and 12 months, respectively.
RESULTSCompared with the healthy controls, the patients with unilateral cryptorchidism showed significant decreases at 12 months in serum AMH (［108.06±12.40］ vs ［103.26±17.57］ ng/ml, P<0.05) and inhibin B (［77.43±5.66］ vs ［70.21±5.69］ pg/ml, P<0.05). No statistically significant differences were found in the length and circumference of the penis and the testis volume in the cryptorchidism side at 6 and 12 months (P>0.05), or in the levels of serum AMH and inhibin B at 6 months (P>0.05).
CONCLUSIONSUnilateral cryptorchidism affects the gonadal function of the patient, and orchiopexy should be timely performed in order to reduce its impact.