New progress in precision diagnosis of prostate cancer.
- Author:
Yue MA
1
;
Yi-Sheng CHEN
1
Author Information
1. Department of Urology / Wuhu Research Institute of Prostatic Diseases, Wuhu Second People's Hospital, Wuhu, Anhui 241000, China.
- Publication Type:Journal Article
- Keywords:
molecular biology;
precision diagnosis;
prostate cancer
- From:
National Journal of Andrology
2016;22(11):1030-1033
- CountryChina
- Language:Chinese
-
Abstract:
The morbidity of prostate cancer presents an obvious ascending tendency. Early diagnosis plays a crucial role in the diagnosis and treatment of prostate cancer. However, the methods widely used for its diagnosis mostly lack high specificity and sensitivity. This review introduces four methods for the detection of prostate cancer, which are PCA3 and TMPRSS2:ERG, the Kallikrein panel, MRGB, and the STHLM3 model, all based on molecular biology and superior to the traditional methods in both specificity and sensitivity. These methods are expected to contribute to the realization of precision diagnosis of prostate cancer.
