Safety evaluation of Rhizoma Dioscoreae bulbiferae and discussion of risk control.
- Author:
Weimin ZHAI
1
;
Li ZHANG
Author Information
1. Chinese Pharmacopoeia Commission, Beijing 100061, China.
- Publication Type:Case Reports
- MeSH:
Dioscorea;
chemistry;
Drug Therapy;
Drug-Related Side Effects and Adverse Reactions;
Drugs, Chinese Herbal;
administration & dosage;
adverse effects;
analysis;
Female;
Humans;
Middle Aged;
Rhizome;
chemistry
- From:
China Journal of Chinese Materia Medica
2010;35(17):2355-2359
- CountryChina
- Language:Chinese
-
Abstract:
Safety literatures on Rhizoma Dioscoreae bulbiferae and oral preparation have been reviewed and analyzed systematically, including textual research for origin and varieties, ancient and modern toxic record and toxic empirical study. Characteristics of clinical manifestations, risk factors and latest findings related to Rhizoma Dioscoreae bulbiferae have been concluded initially. The following measures may be effective for risk control and improving efficacy of Rhizoma Dioscoreae bulbiferae: to develope post-marketed evaluation actively; to regulate clinical medication; to strengthen safety-related basic study including the basis of toxic substances, toxic mechanism, efficacy enhancing and toxicity reducing etc.
