OBJECTIVETo probe into the correlativity of Helicobacter pylori (HP) with cerebral infarction and the possible mechanism.

METHODSComprehensively discuss the data of studies on the clinical correlativity of HP with cerebral infarction and the possible pathogenic mechanisms.

CONCLUSIONMost scholars hold that HP infection is one of risk factors of cerebral infarction. At present, the theory about positive correlation tendency between HP infection and occurrence of cerebral infarction has not been defined. For the mechanism about HP infection possibly inducing cerebral infarction, studies indicate that HP is involved in attack of cerebral infarction possibly alone or via influencing other risk factors, and the pathogenic mechanism mainly include inflammation, immunology and metabolism and so on. However, whether HP infection is a risk factor for attack of cerebral infarction, and the accurate pathogenic mechanisms need further be studied scientifically.