OBJECTIVETo probe into a method for increasing clinical therapeutic effect on renal hypertension of chronic kidney disease.

METHODSOne hundred and fifty-two cases were randomly divided into a combined acupuncture and medicine group and a medication group, 76 cases in each group. The combined acupuncture and medicine group were treated with acupuncture balance points "Jiangya" and "Shenbing" as main, combined with small dose of hypotensor, Irbesartan; and the medication group were treated with oral administration of Irbesartan and Fosinopril. Their clinical therapeutic effects were compared.

RESULTSAfter treatment of 4 weeks, 56.58% of the patients in the combined acupuncture and medicine group reached to the objective value [DBP < or = 84.96 mm Hg (1 mm Hg= 0.133 kPa)], and 53.95% of the patients in the medication group reached to the objective value, with no significant difference between the two groups (P > 0.05). After treatment of 8 weeks and 24 weeks, the blood pressure-decreasing effect in the combined acupuncture and medicine group was better than that of the medication group (P < 0.01). After treatment, protein in the urine decreased and blood creatinine reduced, the clearance rate of endogenous creatinine raised in the two groups, with very significant differences (P < 0.01).

CONCLUSIONAcupuncture combined with small dose of medicine and simple medicine have a same therapeutic effect on renal hypertension of chronic kidney disease, but with prolongation of treatment time, the therapeutic effect and advantages of the combined acupuncture and medicine therapy were superior to the medication.