Recent development on flow cytometric immunophenotyping study in multiple myeloma --- review.
- Author:
Xiao GAO
1
;
Li-Juan CHEN
Author Information
1. Department of Hematology, Nanjing Medical University First Hospital, Nanjing, Jiangsu Province, China.
- Publication Type:Journal Article
- MeSH:
Flow Cytometry;
Humans;
Immunophenotyping;
Multiple Myeloma;
immunology
- From:
Journal of Experimental Hematology
2011;19(4):1083-1086
- CountryChina
- Language:Chinese
-
Abstract:
Multiple myeloma is a common hematological malignancy which is characterized by plasma cell malignancies proliferation and osteolysis destruction. It manifests M-protein, bone destruction, anemia, renal function impairment and immune function abnormality. In recent years, researchers have known that flow cytometric immunophenotyping is valuable in diagnosis, therapy, prognosis and minimal residual disease detection of multiple myeloma. The review summarizes the development of flow cytometric immunophenotyping in multiple myeloma, including application of flow cytometry in multiple myeloma and immunophenotypic features of flow cytometric analysis in multiple myeloma.