Neutrophil ratio/blood glucose and poor short outcome among patients with acute ischemic stroke
10.3760/cma.j.issn.0254-6450.2014.07.023
- VernacularTitle:中性粒细胞比率、血糖水平与急性脑梗死患者短期预后的关系
- Author:
Jiahui WU
1
;
Jintao ZHANG
;
Tan XU
;
Huan ZHANG
;
Yonghong ZHANG
;
Shaoyan ZHANG
Author Information
1. 215123,苏州大学医学部公共卫生学院流行病学教研室
- Keywords:
Acute ischemic stroke;
Neutrophils ratio;
Blood glucose;
Short outcome
- From:
Chinese Journal of Epidemiology
2014;35(7):861-864
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between neutrophil ratio/blood glucose and short outcome among patients with acute ischemic stroke admitted to hospitals.Methods A total of 2 265 acute ischemic stroke patients in four hospitals in Shandong province were included in this study.Through access to patients' files,data on demographic,lifestyle,medical history,family history and laboratory findings were collected from all participants at admission.Endpoint of the study was defined as poor short-term prognosis of acute cerebral infarction (NIHSS≥5) at discharge or death during hospitalization.Subjects of this study were divided into four groups:normal neutrophil ratio with normal blood glucose (NN/NG) ;normal neutrophil ratio with high blood glucose (NN/IG) ;high neutrophil ratio with normal blood glucose (IN/NG) and high neutrophil ratio with high blood glucose (IN/IG).Non-conditional logistic regression analysis was used to evaluate the association between blood glucose/neutrophil ratio and the short outcome of acute ischemic stroke.Results Neutrophil ratio and the level of blood glucose in patients with study endpoints were both higher than those without the study endpoints,and the difference was statistically significant (all P＜0.05). After multivariate adjustment,when compared to NN/NG group,the ORs (95％ CI) of NN/IG,IN/NG and IN/IG group were 1.356 (0.942-1.953),1.879 (1.113-3.171) and 2.210 (1.477-3.307),respectively.Conclusion Neutrophil ratio at admission was an independent risk factor of poor short outcome in patients with acute ischemic stroke.IN/IG group was considered at a highest risk in general population.Neutrophil ratio/glucose was valuable in predicting the incidence of poor short outcome in acute ischemic stroke patients.
