Nonconvulsive Seizures of Traumatic Brain Injury Patients.
10.13004/kjnt.2013.9.2.64
- Author:
Ji Hye LEE
1
;
Jun Seok HUR
;
Hong Joo MOON
;
Ji Hyun KIM
;
Jong Hyun KIM
;
Joo Han KIM
;
Taek Hyun KWON
;
Youn Kwan PARK
;
Heung Seob CHUNG
Author Information
1. Department of Neurosurgery, College of Medicine, Korea University Guro Hospital, Seoul, Korea. jhkimns@gmail.com
- Publication Type:Original Article
- Keywords:
Traumatic brain injury;
Nonconvulsive seizure;
Status epilepticus;
Electroencephalography
- MeSH:
Anticonvulsants;
Aphasia;
Brain Injuries*;
Consciousness;
Diagnosis;
Electroencephalography;
Hospitalization;
Humans;
Incidence;
Retrospective Studies;
Seizures*;
Status Epilepticus
- From:Korean Journal of Neurotrauma
2013;9(2):64-68
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Seizures are common consequence of traumatic brain injury and have been reported in clinical series as an incidence of 15% to 22%. Among them, nonconvulsive seizures (NCS) are often unrecognized during the early period of neurosurgical hospitalization because their clinical presentations can be misunderstood as consequent symptoms of clinical course, and the diagnosis can be confirmed only by the electroencephalographic (EEG) recording. METHODS: We retrospectively reviewed our clinical database of traumatic brain injury (TBI) patients admitted between March 2008 and September 2012. Twenty one patients with suspicious symptoms of NCS, such as decrease of consciousness, aphasia or irritability, were included. Routine wake and sleep EEG or bedside continuous EEG monitoring were done in all patients. RESULTS: Ten out of twenty-one patients showed abnormal activities on EEG. Ictal discharges were documented on four patients. Based on clinical symptoms and EEG findings, these four patients were diagnosed as NCS. Two out of four NCS patients showed EEG findings of nonconvulsive status epilepticus (NCSE). Another six patients with abnormal EEG activities were considered as 'suspicious NCS' because only interictal activities were recorded on EEG but increasing dose or adding on antiepileptics relieved their symptoms. All NCS/NCSE were successfully controlled by appropriate antiepileptic therapy. CONCLUSION: Our result showed that NCS was diagnosed in about 20% of patients with suspicious symptoms. There's a possibility that actual NCS might have happened more. Because untreated NCS/NCSE might cause worse clinical outcome, careful observation and urgent EEG recordings should be considered in a patient with suspicious NCS symptoms.
