A meta-analysis on efficacy of intra-aortic balloon pump therapy in patients with acute myocardial infarction
10.3760/cma.j.issn.0253-3758.2013.05.016
- VernacularTitle:主动脉球囊反搏辅助治疗急性心肌梗死患者疗效评价
- Author:
Xian-Rui ZHANG
1
;
Li SU
;
Shao-Jie CHEN
;
Xiao-Ge ZHANG
;
Yue-Hui YING
Author Information
1. 400010,重庆医科大学附属第二医院心内科
- Keywords:
Myocardial infarction;
Intra-aortic balloon pumping;
Mortality;
Treatment outcome
- From:
Chinese Journal of Cardiology
2013;41(5):432-437
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the efficacy and safety of intra-aortic balloon pump (IABP) therapy in patients with acute myocardial infarction (AMI) based on the meta-analysis.Methods Eligible published randomized controlled clinical research (RCT) were retrieved in the Pubmed,EMBase,Cochrane,China biological medical literature,Wanfang,VIP and CNKI database from 1980 to April 2,2012.The analysis was performed with the software of RevMan 5.1.Results Thirteen RCTs with 1958 patients (AMI with IABP therapy,n =970,without IABP therapy,n =988) were included.The 30-day mortality between the two groups was similar (RR =0.77,95％ CI 0.58-1.03,P =0.08),but the 30-day mortality in the cardiac shock subgroup was significantly lower in IABP group than in without IABP group (RR =0.65,95 ％ CI 0.44-0.97,P =0.04).The 6-month mortality was significantly lower in IABP group than in without IABP group (RR =0.72,95 ％ CI 0.55-0.94,P =0.02).The incidence of major bleeding was significantly higher in IABP group than in withoutIABP group (RR =1.43,95％ CI 1.16-1.75,P ＜0.01).Conclusion IABP therapy is effective to reduce earlier mortality post AMI,particularly for patients with cardiac shock.
