Association between left ventricular diastolic function and blood pressure variability in essential hypertensive patients
10.3760/cma.j.issn.0253-3758.2013.08.012
- VernacularTitle:原发性高血压患者血压变异性与左心室舒张功能的关系
- Author:
Gai-Ling CHEN
1
;
Ming-Jian WANG
;
Jun-Ming LIU
;
Wei XIE
;
Wen-Jun HUANG
;
Yong WANG
;
Yuan-Nan KE
Author Information
1. 中日友好医院心内科
- Keywords:
Hypertension;
Ventricular dysfunction,left;
Ultrasonography
- From:
Chinese Journal of Cardiology
2013;41(8):683-686
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between blood pressure variability (BPV) and left ventricular diastolic function in patients with essential hypertension.Methods Left ventricular diastolic function of 252 hypertensive patients were assessed by early (E) diastolic transmitral flows to early diastolic mitral annular velocity (Ea) (E/Ea) ratio derived from Doppler echocardiography.Patients were divided into two groups according to normal left ventricular diastolic function group (E/Ea ＜ 15,n =168) and left ventricular diastolic dysfunction group (E/Ea ≥ 15,n =84).All patients were monitored by ambulatory blood pressure.Standard deviation (SD) and coefficient of variation (CV) of blood pressure were calculated as the BPV.Relationship between BPV and left ventricular diastolic function were analyzed by multivariate logistic regression analysis.Results All-day average diastolic blood pressure(DBP),the day systolic blood pressure (SBP),night SBP,night DBP,SBPSD,DBPSD and DBPCV in the left ventricular diastolic dysfunction group were significantly higher than in the normal diastolic function group (all P ＜ 0.05).Multivariate logistic regression analysis showed that left ventricular diastolic dysfunction was associated with SBPSD (OR:1.126,95 ％ CI:1.054-1.203,P ＜ 0.01),SBPCV (OR:1.127,95 ％ CI:1.036-1.225,P ＜ 0.01) in this patient cohort.Conclusion High variability of SBP is correlated with left ventricular diastolic dysfunction in hypertensive patients.
