The impact of hypertension history and baseline blood pressure levels on the cardiovascular outcomes in Chinese emergency atrial fibrillation patients
10.3760/cma.j.issn.0253-3758.2013.11.004
- VernacularTitle:高血压病史及基线血压水平对中国急诊心房颤动患者主要心血管事件的影响
- Author:
Juan WANG
1
;
Yan-Min YANG
;
Jun ZHU
;
Han ZHANG
;
Xing-Hui SHAO
;
Li TIAN
;
Bi HUANG
Author Information
1. 100037,北京协和医学院中国医学科学院国家心血管病中心阜外心血管病医院心内科急重症中心
- Keywords:
Atrial fibrillation;
Blood pressure;
Cardiovascular events
- From:
Chinese Journal of Cardiology
2013;41(11):911-915
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of hypertension history and baseline blood pressure levels on cardiovascular outcomes in Chinese emergency atrial fibrillation patients during 1 year followup.Methods This prospective study consecutively enrolled patients presenting to an emergency department with atrial fibrillation from 20 hospitals in China during November 2008 to October 2011.Baseline data and treatment regimen were recorded,all patients were followed up for one year,and major cardiovascular events (MACE including cardiovascular death,stroke,myocardial infarction,and non central nervous systemic embolism) were recorded.Patients were divided into hypertension history group and non-hypertension history group.Univariate Cox analysis was evaluated hypertension history,baseline blood pressure on major cardiovascular events.Multivariate Cox analysis recognized risk factors for major cardiovascular events.Results A total of 2016 atrial fibrillation patients were enrolled,and the average systolic blood pressure and diastolic blood pressure were (131.9 ±23.3)mm Hg(1 mm Hg =0.133kPa),(79.9 ± 14.7) mm Hg respectively.1118 patients (55.5％) had a history of hypertension,and about 91.1％ hypertension patient received antihypertensive treatment.Major cardiovascular events occurred in 314 cases (15.6％) among 1 year follow up,and 191 cases (17.1％) among hypertension group and 123 cases (13.7％) among non-hypertension group.Univariate Cox regression analysis of prognostic factors for major cardiovascular events showed that hypertension history and baseline systemic blood pressure were risk factors (HR=1.269,95％CI:1.012-1.592,P=0.039; HR =1.005,95％CI:1.000-1.010,P=0.042).Multivariate Cox regression model analysis,adjusted others risk factors,showed that hypertension history,baseline systolic pressure levels,and baseline diastolic blood pressure did not have independent predictive value for major cardiovascular events.Moreover,multivariate Cox regression analysis showed that age,history of heart failure,history of stroke were independent prognostic factor for one year follow-up of major cardiovascular events in atrial fibrillation patients.Conclusion Age,history of heart failure,history of stroke were independent predictor for 1 year major cardiovascular events in Chinese emergency atrial fibrillation patients.
