The relationship between myelodysplastic syndromes and autoimmune disorders.
- Author:
Shi ZHAO
1
;
Hong MAO
;
Hongxiang WANG
;
Jie YU
Author Information
- Publication Type:Journal Article
- MeSH: Acquired Immunodeficiency Syndrome; complications; Adolescent; Adult; Arthritis, Rheumatoid; complications; Autoimmune Diseases; complications; Colitis, Ulcerative; complications; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; complications; Predictive Value of Tests
- From: Chinese Journal of Hematology 2002;23(6):311-313
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo explore the relationship between the myelodysplastic syndromes (MDS) and autoimmune disorders (AID).
METHODSThe clinical data of 117 MDS patients were reviewed.
RESULTSNineteen (16.2%) of 117 MDS patients had AIDs. The commonest AID associated with MDS was rheumatoid arthritis (31.6%) and ulcerative colitis (26.3%). Compared with that in MDS patients without autoimmune disorders, the leukemic transformation rate was not increased in the MDS/AID but the median survival time was shorter in MDS/AID patients.
CONCLUSIONMDS patients associated with autoimmune disorders may be an unfavorable factor for their prognosis.
