Relationship between dietary soy isoflavones and blood lipid levels in 40-65 year-olds in Guangzhou
10.3760/cma.j.issn.0254-6450.2009.08.001
- VernacularTitle:广州市40~65岁中老年人膳食大豆异黄酮摄入与血脂关系的横断面研究
- Author:
Bo ZHANG
1
;
Li CAI
;
Meng SU
;
Xiao-Xing ZHOU
;
Li-Li HUANG
;
Chao-Gang CHEN
;
Ren-You CAN
;
Ruo-Qing CHEN
;
Yi-Xiang SU
Author Information
1. 中山大学
- Keywords:
Blood lipids;
Soy isoflavone;
Food-frequency questionnaire
- From:
Chinese Journal of Epidemiology
2009;30(8):761-765
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mlationship between dietary soy isoflavones and blood lipids among residents of 40-65 years old,in Guangzhou.Methods Dietary soy isoflavones and other nutrients intakes were assessed with quantitative food frequency questionnaire(FFQ).Total cholesterol(TC),triglycerides(TG),HDL cholesterol(HDL-C)and LDL cholesterol(LDL-C)in plasma were measured with colorimetry.Results Ranges of dietary soy isoflavones intake among 134 males and 261 females were fxom 0 mg/day to 61.96 mg/day and 0 mg/day to 82.52 mg/day,with means of 11.95 mg/day,14.90 mg/day,respectively.After adjusted for total energy intake and fat percent energy,difiefences of TC,LDL-C in total population and TC in women were statistically significant between groups(P value was 0.002,0.008,0.004,respectively) and dose-effect relationships(P value was <0.001.0.012.0.001,respectively)were observed between dietary soy isoflavones intake and the upper mentioned three indices.Compared with the low-intake group,tbese three indices lowered 7.06%,10.13%and 7.48%,respectively in high-intake group.Critical significance of LDL-C was observed both in women and men between groups.Further controlled for age,BMI and WHR,no obvious change of the results was observed.Conclusion Moderate intakes of soy isoflavone as part of a regular diet seemed to be associated with favorable blood lipid levels.