Research advances in association between pediatric obesity and bronchial asthma.
- Author:
Lian ZHU
1
;
Zhi-Liang XU
;
Yan-Yang CHENG
Author Information
1. Department of Pediatrics, Renmin Hospital of Wuhan University, Wuhan 430060, China. 2661848@qq.com.
- Publication Type:Journal Article
- MeSH:
Asthma;
complications;
Humans;
Leptin;
physiology;
Nerve Growth Factor;
physiology;
Neurotransmitter Agents;
physiology;
Obesity;
etiology;
Plasminogen Activator Inhibitor 1;
physiology
- From:
Chinese Journal of Contemporary Pediatrics
2016;18(7):671-676
- CountryChina
- Language:Chinese
-
Abstract:
This review article introduces the research advances in the pathophysiological mechanism of obesity in inducing pediatric bronchial asthma, including the role of leptin in obesity and asthma, the association of plasminogen activator inhibitor-1 with obesity and asthma, the association of adiponectin and interleukins with obesity and asthma, and the influence of neurotransmitter on asthma. In particular, this article introduces the latest research on the inhibition of allergic asthma through targeting at the nociceptor of dorsal root ganglion and blocking the signaling pathway of the nociceptor.
