Applications of fluorescent molecular imaging in tumor detection.
- Author:
Fei LIU
1
;
Xin WANG
;
Jing BAI
Author Information
1. Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Green Fluorescent Proteins;
metabolism;
Humans;
Indocyanine Green;
Molecular Imaging;
methods;
Molecular Probe Techniques;
Neoplasms;
blood supply;
diagnosis;
Neoplasms, Experimental;
blood supply;
diagnosis;
Neovascularization, Pathologic;
diagnosis
- From:
Journal of Biomedical Engineering
2010;27(5):1152-1157
- CountryChina
- Language:Chinese
-
Abstract:
As a recently emerging molecular imaging technique, fluorescent molecular imaging has the advantage of fast imaging, simple operation, high sensitivity, low cost, nonionizing radiation and so on. Through the real-time, non-invasive, specific tracking and detection of tumorigenesis, metastases, angiogenesis, and the therapeutic response to antitumor drugs in vivo, we can study the physiological and pathological processes within tumors at cellular and molecular levels. Fluorescent molecular imaging provides effective methods for the early detection and targeted therapy of tumor, for the intraoperative visualization of tumor foci, as well as for the development of new antitumor drugs in the future clinical practice.