A Case of Synchronized Pineal and Suprasellar Germinoma.
- Author:
Jae Wook CHUNG
1
;
Jin Ho LEE
;
Soo Jin LEE
;
Chang Young HA
;
Jong Soo KIM
;
Yoon Sok CHUNG
;
Kwan Woo LEE
;
Hyeon Man KIM
Author Information
1. Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
- Publication Type:Case Report
- Keywords:
Pineal and suprasellar germinoma;
Central diabetes insipidus;
Panhypopituitarism
- MeSH:
Diabetes Insipidus;
Diabetes Insipidus, Neurogenic;
Germinoma*;
Headache;
Humans;
Intracranial Pressure;
Lethargy;
Mesencephalon;
Nausea;
Neoplasms, Germ Cell and Embryonal;
Ocular Motility Disorders;
Puberty, Precocious;
Vomiting
- From:Journal of Korean Society of Endocrinology
2000;15(4-5):591-594
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pineal germinomas are the most common intracranial germ cell tumor and occur in relatively young age, with 26% between 10 and 12, 65% between 10 and 21 and 95% before age 27. Patients with pineal germinoma present headache, lethargy, nausea, and vomiting which result from raised intracranial pressure and Parinaud's syndrome secondary to midbrain tectal compression, and rarely endocrine dysfunction such as diabetes insipidus (DI), panhypopituitarism, and precocious puberty. We experienced a case of pineal and suprasellar germinoma presenting with central diabetes insipidus and panhypopituitarism.