Distribution and accumulation of vindoline, catharanthine and vinblastine in Catharanthus roseus cultivated in China.
- Author:
Jinghua YU
1
;
Shusheng YUAN
;
Haihe PANG
;
Xueke ZHANG
;
Xueying JIA
;
Zhonghua TANG
;
Yuangang ZU
Author Information
- Publication Type:Journal Article
- MeSH: Catharanthus; chemistry; growth & development; metabolism; China; Chromatography, High Pressure Liquid; Flowers; chemistry; growth & development; metabolism; Plant Extracts; analysis; metabolism; Plant Leaves; chemistry; growth & development; metabolism; Plant Roots; chemistry; growth & development; metabolism; Seasons; Vinblastine; analogs & derivatives; analysis; metabolism; Vinca Alkaloids; analysis; metabolism
- From: China Journal of Chinese Materia Medica 2010;35(23):3093-3096
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThe content of vindoline, catharanthine and vinblastine in the root, stem, leaf, flower and fruit of Catharanthus roseus at various developmental stages were determined, and the biomass allocation was also determined to find the best harvest time.
METHODThe content of vindoline, catharanthine and vinblastine in the root, stem, leaf, flower and fruit of C. roseus were determined by HPLC.
RESULTThe content of these alkaloids were influenced by season and it varied in the different tissues of the plant. The content of vindoline and catharanthine in the leaves were the highest, and there was no vindoline detected in the root, but the content of vinblastine in the flower was the highest; the content of vindoline and catharanthine reached the maximum between the August and September, and the content of vinblastine reached the highest after the September. The biomass was the highest in the initial stage of September.
CONCLUSIONThe best harvest time was in the initial stage of September.
