Correlation of powder properties and formability of traditional Chinese medicine pellets.
- Author:
Yang HUANG
1
;
Xiaobin JIA
;
Jing ZHU
;
Bin CHEN
;
Hongxia CHEN
;
Qi LIU
Author Information
- Publication Type:Journal Article
- MeSH: Chemistry, Pharmaceutical; Drugs, Chinese Herbal; administration & dosage; chemistry; Particle Size; Powders; administration & dosage; chemistry
- From: China Journal of Chinese Materia Medica 2010;35(23):3136-3139
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the correlation of powder properties and formability of traditional Chinese medicine pellets prepared by extrusion/spheronization.
METHODThe present effort was designed to evaluate the effects of the characters of powder on pellets formation by extrusion-spheronization, taking Danggui Buxue decoction extracts as a model drug and microcrystalline cellulose (MCC) as an ideal balling material for extrusion-spheronization.
RESULTThe diameter of powder had correlation with the plane critical angle of pellets in a certain scope and the sticky coefficient of wet mass affected roundness of pellets.
CONCLUSIONProperties of powder have influence on formability of traditional Chinese medicine pellets.
