Chemical constituents of Swertia macrosperma.
- Author:
Hongling WANG
1
;
Changan GENG
;
Xuemei ZHANG
;
Yunbao MA
;
Zhiyong JIANG
;
Jijun CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Plant Extracts; analysis; isolation & purification; Swertia; chemistry
- From: China Journal of Chinese Materia Medica 2010;35(23):3161-3164
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Swertia macrosperma.
METHODThe air-dried whole plants of Swertia macrosperma were extracted with boiling water. The extract was concentrated to a small amount of volume and extracted with petroleum ether, EtOAc and n-BuOH, successively. The compounds were isolated and purified by column chromatography from the EtOAc fraction, and identified based on spectral analyses (MS, 1H-NMR, 13C-NMR).
RESULTThirteen compounds were isolated from S. macrosperma, and were characterized as norbellidifolin (1), 1-hydroxy-3,7, 8-trimethoxy-xanthone (2), norswertianolin (3), swertianolin (4), 1,3,7,8-tetrahydroxyxanthone-8-O-beta-D-glucopyranoside (5), swertiamatin (6), decentapicrin (7), coniferl aldehyde (8), sinapaldehyde (9), balanophonin (10), together with beta-sitosterol, daucosterol, and oleanolic acid .
CONCLUSIONCompounds 2, 4-10 were obtained from Swertia macrosperma for the first time.
