In silico pharmacology of Chinese herbs for chronic kidney diseases.
- Author:
Wei ZHU
1
;
Dinghong WU
;
Xiaohui QIU
;
Wen XU
Author Information
1. Guangdong Hospital of Traditional Chinese Medicine, Guangzhou 510106, China. zhuwei9201@163.com
- Publication Type:Journal Article
- MeSH:
Chronic Disease;
therapy;
Drugs, Chinese Herbal;
adverse effects;
chemistry;
pharmacology;
Humans;
Kidney Diseases;
drug therapy
- From:
China Journal of Chinese Materia Medica
2010;35(23):3211-3215
- CountryChina
- Language:Chinese
-
Abstract:
Tonifying herbs and evil expelling herbs of traditional Chinese medicine (TCM) for chronic kidney diseases in molecular level were studied by computer aided drug design, including analysis of molecular similarity, predictive ADME simulation and predictive toxic simulation. It was found that this technology could distinguish the structure diversity of compounds from TCM, and screen the lead compounds rapidly.
