Dynamic extraction process of salvianolic acids.

Author: Lingqiao LU ¹ ; Yongchuan ZHOU ; Xian CHEN ; Min ZHANG ; Jieting DAI
Author Information

1. Engineering Center for Traditional Chinese Medicine Modernization, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Publication Type:Journal Article
MeSH: Benzofurans; analysis; isolation & purification; Chemical Fractionation; methods; Drugs, Chinese Herbal; analysis; isolation & purification; Temperature
From: China Journal of Chinese Materia Medica 2010;35(22):2976-2979
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo optimize the dynamic extraction process of salvianolic acids.
METHODSalvianolic acids was selected as index. The effects of extraction temperature, granularity, solvent multiple, circle value and extraction time were studied on the process of dynamical extraction. The orthogonal experiment was employed to investigate the influence of different parameters.
RESULTThe optimal extracting method of salvianolic acids was as follows: temperature was 80 degrees C, granularity was 4 mm, circle value was 30 L x h(-1), solvent multiple was 10 times and extraction time was 150 min.
CONCLUSIONBy comparison to static extraction, dynamic extraction can improve the extraction efficiency, reduce the solvent and energy consumption, as well as lower the burden of post-processing.