Effect of congrong powder preparation on erythrocyte parameter and index of blood rheology in rats.
- Author:
Zhengran LIU
1
;
Dong ZHANG
;
Haijun WU
;
Yueling LI
;
Shiping CHEN
;
Yumei YANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Viscosity; drug effects; Drugs, Chinese Herbal; pharmacology; Erythrocyte Deformability; drug effects; Erythrocytes; drug effects; Male; Powders; pharmacology; Random Allocation; Rats; Rats, Wistar
- From: China Journal of Chinese Materia Medica 2010;35(22):3074-3076
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of Congrong powder preparation on erythrocyte parameter and the index of blood rheology in healthy rats.
METHODThe 50 rats were randomly divided into 5 groups ( physiological saline group, testosterone propionate group, large-dose administered group, moderate-dose administered group, small-dose administered group). Blood were taken to determine erythrocyte parameter and the index of blood rheology.
RESULTCongrong powder preparation had no effect on erythrocyte parameter. There was an increase in whole blood viscosity, whole blood reduction viscosity, and in the erythrocyte rigidity index in the large-dose administered group.
CONCLUSIONCongrong powder can influence deformability and some related characters of erythrocytes.