Surgical treatment for hemophilic pseudotumor in maxillofacial region

VernacularTitle:颌面部血友病假性肿瘤的外科治疗
Author: Zhi-Ping LI ¹ ; Jian MENG ; Jie ZHANG ; Ai-Xia ZHANG ; Qian-Ping GU
Author Information

1. 徐州市中心医院口腔颌面外科
Keywords: Hemophilia A; Cysts; Factor Ⅷ
From: Chinese Journal of Stomatology 2013;48(1):12-14
CountryChina
Language:Chinese
Abstract: Objective To present 4 cases of hemophilic pseudotumor and to investigate the treatment outcome.Methods Four cases of hemophilic pseudotumor were reviewed.The patients were treated by internal medicine combined with surgery and followed up for two years.The feature and diagnosis of the disease were analyzed and the treatment outcome was evaluated.Results All of the 4 cases were misdiagnosed with a history of bleeding before operation.One patient was bleeding after biopsy without replacement therapy.One patient was presented with gingival bleeding and anaemia.The final diagnosis of hemophilia A in all the 4 cases was confirmed by the blood test(Ⅷ deficiency).After infusion of factor Ⅷ,operation was performed on all cases.There was no recurrence after two years of follow-up.Conclusions It should be aware of the rarely encountered disease which is prone to be misdiagnosed.Under factor-deficient replacement therapy,surgical management is the most effective way in preventing from bleeding and avoiding progressive expanding of pesudotumor.